The programs currently employ about 800 people in Southern California. About 550 of those positions will be relocated to Oklahoma City. Boeing says other positions will be hired locally in Oklahoma City.
"Making a decision like this is never easy, but as we reviewed our anticipated operating costs for the next several years, it became clear that Boeing needs to take major actions on these programs in order to remain affordable for our customers," MM&U Vice President and General Manager Mark Bass said in a statement.
Boeing says it will help employees who do not make the transition look for other jobs within the company.
The company is headquartered in St. Louis.