Researchers found that three loci, or locations on the chromosome, had a much stronger link to susceptibility than the others, and a fourth approached "genome-wide significance," according to a news release.
These particular loci are associated with the most aggressive and common of the four main types of ovarian cancer.
Researchers say the discoveries move them a closer to individualized risk assessments for ovarian cancer.
The findings appear in Nature Genetics.
Ovarian cancer accounts for more deaths than all other gynecological cancers combined.
For more information:
http://www.mayoclinic.org/news2010-rst/5943.html
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.668.html