No date was given for the Jacksons' interview. Katherine Jackson will talk about her son's life from childhood stardom to his death, according to Harpo Productions. She'll be joined by her husband, Joe Jackson.
Harpo released the schedule Friday.
On Nov. 2, Ricky Martin will talk about raising twin boys and his decision to come out as gay.
This is the 25th and final season of Winfrey's talk show.
The Associated Press contributed to this report.