Lake Forest came in seventh and Irvine was tenth.
The safest U.S. city was Colonie, N.Y, near Albany.
Conversely, one Southern California city made the list of the most dangerous in the U.S.
Compton was ranked the eight most dangerous city in the nation.
St. Louis was the most dangerous American city overall.
The rankings are calculated based on rates of major crimes like murder, rape and robbery.