The crash caused street closures near the 55 Freeway while police investigated.
It was not clear what led to the crash.
Anyone who witnessed the crash is asked to call police at (714) 834-4211.
The Orange County Register contributed to this report.
Woman crashes into big-rig, critically injured
SANTA ANA, Calif. According to Santa Ana Police, the woman was driving on Pullman Ave. near Garry Ave. in a Ford Focus when she struck the parked truck. No one was in the truck.
