The two novels are being issued in a single bound paperback edition of about 800 pages with a list price of $20. An electronic version is available for $7.99. It can also be downloaded for free through the new Google bookstore.
Winfrey said on Monday's show that she has never read Dickens before. She said, "It's the best of times, readers," and called the books timeless classics.
Winfrey has previously selected classic books including, Leo Tolstoy's "Anna Karenina" and John Steinbeck's "East of Eden."
The talk show queen also hosted famed fiction author Jonathan Franzen on her Monday show. Oprah chose his bestselling novel "Freedom" for her book club in September.
Oprah's Book Club has nearly 2 million online members, according to Harpo Productions. Winfrey has said she will take the book club with her when she moves to her new cable station, the Oprah Winfrey Network, which launches Jan. 1.
The Associated Press contributed to this report.