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Pain killers may reduce antidepressant effectiveness

April 26, 2011 12:00:00 AM PDT
Some common over-the-counter pain relievers may reduce the effectiveness of anti-depressants, according to a new study.

Researchers treated mice with anti-depressants in the presence or absence of pain-reducing drugs.

They said the animals' behavioral responses to anti-depressants were inhibited by anti-inflammatory drugs.

Researchers confirmed these same results in humans.

The findings suggest that doctors should carefully look at the advantages and disadvantages of continuing anti-inflammatory therapy with patients who are depressed.