The six crewmembers - led by Mark Kelly, the husband of wounded congresswoman Gabrielle Giffords - arrived at Kennedy Space Center a day before the countdown clocks begin ticking again.
Endeavour is set to blast off Monday morning.
The first launch attempt on April 29 was scrubbed due to electrical trouble. In brief remarks after the crew's arrival, commander Mark Kelly said the launch director has assured him that Endeavour is "in great condition."
Giffords is planning to return to the Kennedy Space Center to see next week's launch. According to her staff, she will return to Houston to continue rehab shortly after liftoff.
Aboard Endeavour is a $2 billion particle physics detector that will be attached to the space station.
The Associated Press contributed to this story