The gunfire erupted in the 5000 block of 112th Street at about 12:45 a.m. Monday.
The victims were at a party and enjoying fireworks when the shots were fired. All six people were taken to area hospitals with non life-threatening injuries.
They were treated and released.
Authorities said the gunman was a male in a dark colored car.
Anyone with information about the shooting is urged to call the Los Angeles County Sheriff's Department's South L.A. Station at (323) 820-6700.