All of the proceeds from the event go to Project Angel Food.
From designer handbags to beauty products, there are a variety of items offered for at least 50 percent off.
Also available at Divine Design are Feed Bead bracelets, which were handmade by volunteers of Project Angel Food. They are $5 each, and for every $5 spent in the marketplace, one meal is donated to a person with a life-threatening illness.
This is the 20th anniversary of the event.
"It's so popular because we have great stuff ... it really tickles people in a profound way that every dollar they're spending here on great designer stuff is actually feeding people with life-threatening illnesses," said Alex Boling of Project Angel Food.
Last year, Project Angel Food cooked and delivered more than 735,000 meals for people with life-threatening illnesses. Boling said the goal this year is to create even more meals.
The event opens on Friday and runs through Monday from 10 a.m. to 8 p.m. For more information, visit http://www.divinedesign.org/.