They demonstrated outside Edison offices in Rosemead over the longstanding dispute.
The high-voltage transmission lines are part of the Tehachapi Project to generate more renewable energy.
Some residents are worried that property values will suffer. Others have expressed concerns over health and safety.
"This project is ill-conceived, it is ill-advised. We feel like we're being treated as lab rats for Edison because of the 500 kilovolt lines that they're planning to run within 70 feet of homes," said Chino Hills resident Bob Goodwin.
"Southern California Edison understands that residents in Chino Hills don't like transmission lines next to their backyards," said SoCal Edison spokesman Alis Odenthal. "However, the Tehachapi Project is being built to help satisfy the state's renewable resources requirements of 33 percent."
Opponents want Edison to reroute the lines through a nearby state park instead.
The California Public Utilities Commission has asked Edison to prepare additional information about potential alternatives. Edison says it will provide that on January 10.