The incident took place just after 2:30 a.m. near 84th and Hoover streets at a house party.
One man was killed at the scene and two people were injured. The injured were taken to a nearby hospital, where their conditions were unknown.
Police were trying to figure out a motive for the shooting but say the victims may know the gunman. Authorities say the shooting does not seem to be gang related. The shooter remains at large.
If you have any information regarding this incident, you're urged to call the Los Angeles Police Department at (877) LAPD-24-7 or (877) 527-3247.