The incident happened at Sixth Street and Towne Avenue at about 5:30 p.m. Wednesday.
Police said an SUV slammed into the bicycle rider at that intersection and dragged him for about half a block. He died at the scene from his injuries.
The driver did not stop.
Witnesses described the hit-and-run vehicle as a green Dodge or Chrysler SUV.
If you have any information about the crash, you're urged to call Pomona police at (909) 622-1241.