Tatum and Hill were the executive producers of the film, which earned an estimated $35 million in its opening weekend. The action comedy depicts Hill and Tatum as cops who pose as high school students to root out crooks peddling a psychedelic new drug at a Los Angeles school.
"Dr. Seuss' The Lorax," finished in second place with nearly $23 million. Prior to the debut of "21 Jump Street," "The Lorax" held the No. 1 box office spot for two consecutive weeks. Disney's "John Carter" was third with $13.5 million, while "Project X" and the comedy, "A Thousand Words" with Eddie Murphy rounded out the top five.
The top films of the weekend were:
1. "21 Jump Street," $35 million ($7 million international).
2. "Dr. Seuss' the Lorax," $22.8 million ($11.6 million international).
3. "John Carter," $13.5 million ($40.7 million international).
4. "Project X," $4 million ($5.6 million international).
5. "A Thousand Words," $3.8 million.
6. "Act of Valor," $3.7 million.
7. "Safe House," $2.8 million ($3.5 million international).
8. "Journey 2: The Mysterious Island," $2.5 million ($5 million international).
9. "Casa de mi Padre," $2.2 million.
10. "This Means War," $2.1 million ($9.2 million international).
The Associated Press contributed to this report.
