The LAPD says the accident happened at about 8:55 p.m. near the intersection of Cahuenga and Lankershim boulevards in Universal City.
After she was hit, a second vehicle also struck the victim, who was in her 50s. That driver stopped and was questioned by investigators.
The car responsible was last seen speeding away north on Cahuenga. The vehicle is only described as a 4-door sedan with heavy front-end damage.