Firefighters responded to the 12000 block of West National Boulevard around 8:33 p.m. and found a female suffering from a stab wound in the abdomen.
The victim was transported to a local hospital and is expected to survive.
Police say the suspect took a computer from the residence and may have been driving a white pick-up truck.
LAPD officials were canvassing the industrial area and gas station near the victim's home because they believe she may have been followed.
Anyone with information was urged to call police at (877) LAPD-24-7.