The crash was reported around 10:30 p.m. at Central Avenue and 120th Street. Authorities said a motorcyclist rear-ended the cruiser. The rider was thrown off the bike. The motorcycle continued southbound and rear-ended another car.
The motorcyclist was transported to a local hospital in unknown condition. Investigators said the deputy, who is from the sheriff's Century Station, did not suffer any serious injuries.
The Los Angeles Police Department is investigating the cause of the crash.