The crash happened at about 3 p.m. at the intersection of Avenue K and Sierra Highway, according to sheriff's officials.
The deputy was going southbound on Sierra Highway and through the intersection when he was struck on the side by a driver going eastbound.
The patrol car then collided with two other vehicles. A total of four cars were involved in the wreck.
The driver of the patrol vehicle was transported to a hospital with minor injuries. No one else was hospitalized, officials said.
No arrests were immediately made.