Family members identified the man as Tyler Honeycutt, a former UCLA basketball player who had a brief career in the NBA.
Overnight, Los Angeles Police Department SWAT officers went into the home and discovered the man's body, police said in a tweet shortly before 4 a.m.
Authorities tweeted later that it appeared Honeycutt died from a self-inflicted gunshot wound.
UPDATE: Regarding last nights Officer-Involved Shooting in Van Nuys Division, it appears as if the suspect was not struck by any officer’s gunfire. The suspect appears to have sustained injuries consistent with a self-inflicted gunshot wound.— LAPD HQ (@LAPDHQ) July 7, 2018
The barricade began about 5 p.m. Friday, when police received a call from the suspect's mother, who said her son was acting erratically.
When officers arrived at the home, near Riverside Drive and Tyrone Avenue, the suspect opened fire on them, authorities said.
Officers returned fire, and the suspect barricaded himself inside the home for several hours.
No officers were injured in the shooting, authorities said.
At least 30 residents surrounding the home were evacuated as a precaution.
An investigation is ongoing.