Three of the Marines who died were from the Inland Empire and a fourth lived in Orange County.
A bell was tolled 13 times to honor each of the lives lost.
"It hit home," said Murrieta resident Ron Rodriguez. "All my fellow vets. People need to understand. Don't disrespect the flag. Ths country is made up of everybody and that's what everyone sacrificed for, for this country."
Inland Empire Marines killed in the attack were: Kareem Nikoui, 20, of Norco, Hunter Lopez, 22, of La Quinta, and Dylan Merola, 20, of Rancho Cucamonga.
Marine Staff Sgt. Darin Taylor Hoover, 31, who lived in Aliso Viejo, was also killed in the bombing. He had served in the Marines for 11 years.
"Anyone that has kids knows what it would be like to say goodbye to a child," said Sharon Van Druff of Canyon Lake. "I think it would probably be one of the hardest things that would ever happen."
Another ceremony is planned for Thursday in Rancho Cucamonga to honor Merola.
All 13 military members killed in Kabul attack identified
The emotional memorial service came as President Joe Biden officially declared an end to America's longest war.
Shortly after the last U.S. servicemember left Afghanistan, the Taliban moved in to take full control of the airport and a hanger full of vehicles and aircraft which the Pentagon says were left inoperable.
As the Taliban declares victory, work continues to get up to 200 Americans left behind out.
Facing a barrage of criticism over the chaotic and deadly evacuation the president is defending his decision to pull out all US troops.
"We were left with a simple decision," Biden said. "Either follow through on the commitment made by the last administration and leave Afghanistan. Or say we weren't leaving and commit another tens of thousands of troops going back to war."