The inferno was burning at a structure on Lester Avenue, near Lake Merritt, in a densely populated residential area.
The building had been under construction and no one was living in the building, fire officials confirmed.
There are no immediate reports of injuries.
The cause of the fire was unknown.
Oakland firefighters say they will be at the scene of this huge fire all day watching for hot spots. pic.twitter.com/h5hoZfvZfn— Amy Hollyfield (@amyhollyfield) October 31, 2016
There's a big fire in Oakland near Lake Merritt. This is insane. pic.twitter.com/hd0qsZeSjk— Dave Guarino (@allafarce) October 31, 2016