The crash happened shortly after 7:30 a.m. at 119th Street and Willowbrook Avenue.
County fire officials said one person was hospitalized in unknown condition. It wasn't immediately known if the injured person was in the car or train.
Blue Line service was suspended on that stretch of track and buses were sent to pick up passengers.
Metro says delays are expected on northbound and southbound lines.
BLUE LINE: Major delays continue due to train-auto incident btwn Willowbrook/Rosa Parks-Compton. Bus shuttles established. Allow extra time.— Metro Rider Alerts (@metrolaalerts) November 23, 2015
The cause of the collision is under investigation