Michael Anthony Cuellar, 29, and Sierra Tarbutton, 27, have been charged with deadly conduct, a felony offense, but are not in custody.
Residents were on edge after the video went viral on social media.
Three different videos on Snapchat appear to show a man and a woman shooting out of a vehicle in a flood-damaged neighborhood of Houston, according to Reddit user "HARRISCORES."
One homeowner joked that her home in the Fleetwood neighborhood was already damaged by flooding from Hurricane Harvey, so one more bullet wouldn't make a difference.
"The house is already destroyed, one more bullet hole won't hurt - but it's just scary," said a homeowner, who asked to only be identified as Sally. Her joke, understandably, seems to cover frayed nerves.
The wall that protects her home from Memorial Drive was lost to Harvey floodwaters.
Anyone with information about the suspects' whereabouts is asked to call Houston Police Department at 713-884-3131 or Crime Stoppers at 713-222-8477.