Authorities say deputies were serving an eviction notice at 2330 Cahuenga Boulevard around 7 a.m. when they heard a gunshot inside the apartment.
Deputies backed away, and a SWAT team rushed to the scene. Crisis negotiators attempted to make contact with the barricaded suspect.
The situation forced law enforcement officials to shut down the 101 Freeway in both directions for hours. Authorities were concerned about possible gunshots coming from the apartment's balcony.
AIR7 HD was over the scene as authorities sent a drone up to the window of the unit where the individual was believed to holed up.
Shortly after 1 p.m., authorities announced that the suspect, who has not yet been identified, was found dead from what investigators described as a self-inflicted gunshot wound.
Neighbor Trevor Marsh said he noticed an eviction notice attached to the door a couple weeks ago, which was not removed. He added that there was also a notice about a rent increase that was left attached to the door from a few months ago.
The 101 Freeway has since fully reopened.