Their first flight mission was on Sunday.
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"We actually flew off the coast of California up to about 32,000 feet and did 15 parabolic maneuvers in which we experienced the joy and wonder of micro gravity," said George Whitesides, the co-project lead of AstroAccess.
The participants practiced mobility, visual and audio cues.
"You know it was great floating and not looking up from the ground. I don't really look up from my chair anymore because I have an elevator, but still for many years I didn't have that," said Dana Bolles, a flight participant.
Participants say the opportunity to go to space is available to more people now, so it's important that it's accessible for everyone.
"For the deaf community, I think this was a big challenge because when you're trying to sign in zero g, you can't stop yourself. You're moving, so you're kind of moving as you're talking and then you have to stop signing and push off the wall," said Apurva Varia, a flight participant.
The participants talked about what could be done to make space travel easier for disabled people.
"I think something that would be really helpful is like a foot rail that I think could've been a really helpful design especially one I'd be able to adapt for my prosthetic leg," said Mary Cooper, a flight participant.
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All of the participants had one universal message for others who may be disabled.
"Don't accept no if that's something you really want to do because you're capable," said Bolles.
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