The first crash occurred on westbound lanes around 2 a.m. at Buena Vista Street and involved what appeared to be an Amazon truck that overturned. All but one lane was closed.
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As crews were working to clear that wreck, another incident happened just feet away on the east bound lanes.
That crash involved a motorcyclist and another semi-truck. The person on the motorcycle was taken to the hospital.
It's unclear when lanes on either side of the freeway would be reopened, but a massive backup of cars was seen in the area.
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Details about what led up to either crashes were not immediately available.
DEVELOPING: We will add more details to this report as they become available.