The crash happened just before 5 a.m. at Mulholland Drive when a vehicle traveling up the hill somehow apparently swerved and collided into the back of a semi-truck that was parked on the shoulder.
It's unclear what caused the crash, but that driver died at the scene.
Crews on scene worked through the morning to clear the wreck, causing significant delays to drivers. All freeway lanes were reopened by around 11 a.m.