Trebek announced in March 2019 that he was diagnosed with stage 4 pancreatic cancer and has since become an outspoken advocate, raising awareness about the disease and the symptoms.
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Referring to the moment he was diagnosed, the television personality said he knew the news was bad when his doctor mentioned the pancreas. All stages of pancreatic cancer combined have an overall 9% five-year survival rate, according to reports by the American Cancer Society.
"Throughout my life, I've always wondered about how courageous a human being I was ... I just look at it as, it's part of life ... does that mean I'm courageous because I'm dealing with it? No. I could be scared to death, and I'd still have to deal with it. But I'm not scared to death. So maybe I am courageous. Way to go, Alex!"
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Jean Trebek, the game show host's wife of 29 years, said the hardest part for her is seeing her husband in pain. Alex also admitted that Jean has a tough job as a caretaker, always worrying about his wellbeing.
"I'm not always the most pleasant person to be around when I'm experiencing severe pain or depression. She has to tread lightly around me," he said.
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She said she sometimes wishes he would take a break from his career but knows "it's what feeds him."
"He loves doing 'Jeopardy!' He has his own family over there," Jean Trebek said. "They're such a close-knit, beautiful group of people, so I think that gives him a lot of support, a sense of purpose, that he's just not in bed."
Yet Alex said one of the most powerful influences on his positive outlook is his fans.
The host said his original intention for telling the world about his diagnosis was to get "ahead of the tabloids" but he had no idea his announcement would have such an impact on people around the world.
"Most of us have open-ended lives. We don't know when we're going to die. Because of the cancer diagnosis, it's no longer an open-ended life, it's a closed-end life because of the terrible statistics, survival rates for pancreatic cancer," he said. "And because of that, and something else that is operating here, people all over America and abroad have decided they want to let me know now, while I'm alive, about the impact that I've been having on their existence ... They have come out and they have told me. And, my gosh, it makes me feel so good."