A company spokesperson said Bud Light's Vice President of Marketing took a leave of absence after she was targeted by conservative pundits.
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The partnership between the beer brand and Dylan Mulvaney, who has more than 10.8 million followers on social media, hit the internet on April 1.
That's when Mulvaney posted a video on Instagram showing herself cracking open a can of Bud Light, one with the hashtag #budlightpartner.
Earlier this month, Bud Light said, "Anheuser-Busch works with hundreds of influencers across our brands as one of many ways to authentically connect with audiences across various demographics."
But the Bud Light-Mulvaney partnership quickly brought an onslaught of criticism from people, many with anti-transgender views, who have called for a boycott of the beer maker. Mulvaney spoke out about the issue on Thursday in a video posted to her Instagram.
"I grew up in a conservative family, and I'm extremely privileged because they still love me very much, and I grew up in the church, and I still have my faith, which I am really trying to hold onto right now," she said. "But I've always tried to love everyone, you know? Even the people who make it really, really hard and I think it's okay to be frustrated with someone or confused, but what I'm struggling to understand is the need to dehumanize and to be cruel."
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There have been reports that the company has since seen a drop in sales since the collaboration.
Anheuser-Busch has not confirmed that information.
According to the Associated Press, Anheuser-Busch InBev's stock that trades in the United States is down 1.8% since Mulvaney's April 1 video. But the stock is still up 9.1% for the year so far, more than the broad U.S. stock market, as measured by the S&P 500.
The Associated Press contributed to this report.