The violent collision was reported shortly before 2 p.m. in the Badlands area of Riverside County, about halfway between Beaumont and Moreno Valley, according to the California Highway Patrol.
A white Corvette convertible and a black Audi SUV were also involved in the pileup. Aerial video from AIR7 HD showed significant damage to those vehicles.
The cause of the crash was not immediately known. All lanes of the 60 Freeway were reopened shortly before 5 p.m.