According to the Metro Cities Fire Authority, calls began coming in about a fire at a single-story commercial building at 1169 N. Knollwood Circle just before 11:30 a.m.
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Authorities tell Eyewitness News a total of three people were injured, including two firefighters who suffered injuries due to an explosion that occurred.
They were treated at UCI Medical Center in Orange and have since been released from the hospital. Officials say they're expected to be OK. One of the firefighters suffered second-degree burns to his face, and the second suffered a back injury when he was blown into his air tank from the explosion, police said.
Sgt. Steve Pena of the Anaheim Police Department said a suspect was severely injured during the process and rushed to an area hospital.
"It looks like they were doing some sort of honey extraction -- making hash oil (and) doing a chemical process with marijuana,'' said Pena.
He added that a second suspect, who was not injured, was arrested, "and, so far, he's cooperating with our investigation.''
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Firefighters from the Orange County Fire Authority and the Orange and Fullerton fire departments were assisting in the effort.
The incident remains under investigation.
The location of the fire is about two miles east of the theme park. Video submitted to ABC7 by a visitor showed a large plume of smoke visible from the park.
City News Service, Inc. contributed to this report.