Deputies responded to the 8400 block of Serapis Avenue around 1:15 a.m. and found two adult suspects suffering from gunshot wounds, authorities said.
The homeowner opened fire on one of the suspects who broke into the residence through a window, wounding the suspect, according to the department.
The homeowner then stepped out onto his back patio, where he confronted the second suspect, who he believed was reaching for a firearm. The second suspect, who has not been identified, was shot and killed.
A getaway driver who took the wounded suspect to an area hospital was taken into custody. The wounded suspect was undergoing surgery, according to a detective.
The sheriff's department did not release any additional details.