The so-called Lobo Fire was reported shortly before 1 p.m. near the intersection of Parkway Calabasas and Calabasas Road. Almost an hour later, it had spread to about six acres.
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There were no immediate reports of injuries or structures threatened.
Los Angeles city and county firefighters responded to the scene as part of a mutual aid agreement, along with sheriff's deputies from the Lost Hills station.
At least one air tanker was seen dumping red Phos-Chek on the flames.
At 5:33 p.m., the city of Calabasas said the fire was 75% contained, but expects more forward spread.
Conditions in the area were marked by 96-degree temperatures and relative humidity of 18%, with wind gusts up to 12 mph, according to the L.A. County Fire Department.
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The cause of the fire is unknown.