"BNSF Railway can confirm that a train carrying corn syrup derailed" around 7:40 p.m., company spokesperson Lena Kent told CNN in an email. "There were no injuries as a result of the derailment and preliminarily reports indicate there are no hazardous materials involved."
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The derailment happened in Mohave County, Arizona, near the state's border with California.
A spokesperson for the Mohave County Sheriff's Office earlier said the train was reportedly carrying hazardous materials.
No spills have been reported, though there are washes running through the area from recent storms, Anita Mortensen, a spokesperson for the sheriff's office, said.
The derailment occurred near milepost 9 of Interstate 40, Mortensen said, which is a rural, non-residential area. The highway exit is home to a handful of truck stops and is about 20 miles north of Lake Havasu City.
An estimated eight cars derailed and are blocking the main track, according to Kent. The cause of the derailment is under investigation and it's not clear when the track will reopen, the freight railroad company said.
The derailment comes a week after another train careened off the tracks in rural West Virginia, injuring three crew members and spilling diesel fuel into a nearby river, and over a month after a fiery derailment in East Palestine, Ohio, released potentially hazardous chemicals into the air, soil and water and required extensive cleanup efforts.
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The National Transportation Safety Board has been notified of the incident and is responding to investigate, Mortensen said.
CNN has sought comment from the NTSB.
Correction: An earlier version of this story incorrectly described what the train was carrying. It was carrying corn syrup, but no hazardous materials, according to BNSF Railway.
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