The winning ticket matched all six numbers and was sold at Spring Valley Market in Victorville.
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Five other tickets matched five numbers, but missed the Mega number. They are each worth $13,324.
The winning numbers are: 17, 19, 23, 31, 33 and the Mega number was 14.
The drawing was the 76th since the last time a ticket with all six numbers was sold.
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Wednesdays' drawing is expected to be worth $7 million.
The odds of matching all five numbers and the Mega number is 1 in 41,416,353, according to the California Lottery.
City News Service contributed to this report.