The incident unfolded at 14500 Chere Drive, just south of Telegraph Road.
[Ads /]
The sheriff's department told Eyewitness News the two suspects were shot and rushed to the hospital.
Their condition is unknown. A third suspect was also apprehended.
One deputy was also sent to the hospital and another - who was off duty at the time - refused to seek treatment. Authorities tell Eyewitness News the deputy's injuries are considered minor.
[Ads /]
It's unclear what prompted the shooting or what the suspects were wanted for, but AIR7HD video showed a car riddled with bullet holes at the scene.
Anyone with information is urged to contact the L.A. County Sheriff's Department's Homicide Bureau at 323-890-5500.