The incident began when a deputy responded to a report of a burglary in the 1200 block of South Brannick Avenue.
The suspect fired at least one shot at the deputy, prompting a barricade situation as a SWAT team was summoned to the scene. There were no immediate reports of any injuries.
Residents of nearby homes were evacuated and all southbound lanes on the nearby 5 Freeway were briefly closed. The lanes were reopened but the Olympic Boulevard offramp remained shut down.
Surrounding streets in the residential neighborhood were also closed to traffic as the standoff continued.
The suspect was barricaded in the second floor of the home for several hours, but was taken into custody by early afternoon.