The crash was reported around 3 a.m. The taxi driver died at the scene and there was one passenger in the taxi taken to the hospital with major injuries.
The car going the wrong-way was a Chevy Cruze. Both passengers of that car were also taken to the hospital with major injuries.
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The lane closure caused traffic delays going northbound starting around South L.A.
CHP reopened the lanes around 6 a.m.
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The identities of the victims have not been released.
This is a breaking news story. Check back for more details.