It happened Tuesday around 5:30 p.m. near a used car lot on San Fernando Road.
It's unclear what led up to the shooting but witnesses said they heard people arguing before gunfire erupted. One of the victims died at the hospital while the other remains hospitalized in an unknown condition, police said.
Investigators said the suspect fled the scene, possibly in a white Nissan Armada SUV.
Anyone with information is urged to contact authorities.