The California Highway Patrol shut down several lanes of the eastbound side of the freeway near Hayvenhurst Avenue in Granada Hills.
Drivers should expect delays and seek alternate routes. It's unknown how long the partial closure will last.
The fire broke out shortly before 9 p.m. At least one acre was burned, according to officials.
AIR7HD captured a resident up on a roof with a hose out, watering a tree next to their home making sure no embers caught their roof on fire.
Despite 10 mph winds, dozens of firefighters were able to stop the forward progress of the Granada Hills fire in one hour, according to the Los Angeles Fire Department.
The agency also reported a second brush fire burning adjacent to the 118 Freeway and Reseda Boulevard in Porter Ranch. That fire broke out just after 8:30 p.m.
It took about an hour and 74 firefighters to stop the forward progress of the Porter Ranch blaze, LAFD said. No structures were damaged.
Officials don't believe at this time that the two fires are related.
Firefighters will remain at the scene of both fires to "continue containment and overhaul," officials said.
No injuries have been reported.
The cause of the fires is under investigation.