The burglary happened just before 4:30 a.m. in the 5400 block of N. Figueroa Street, according to the Los Angeles Police Department.
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The business lost approximately $8,600 worth of merchandise, police said.
The shop owner and police now hope someone will recognize the suspects from the surveillance video.
Security cameras captured the thieves - who were wearing dark-colored hoodies and face masks - break a glass door and force themselves in. Police say they also used an electric saw to cut open a metal fence.
Another camera captured one of the suspects in the storage room taking cash from a drawer and stuffing it into his pockets. The suspects also grabbed merchandise and tossed it into plastic bags.
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Video showed the suspects run back to the front door and escape in a silver Infiniti sedan.
The owner says they stole cash, cartons of cigarettes and more items from the storage room.
The LAPD is investigating the break-in. No arrest has been made so far.