Elfman, best known for her role on "Dharma & Greg," had told her agents she didn't want to do a network primetime comedy this year. But then she heard about "Imaginary Mary" and signed right up.
The ABC show features Elfman as a 30-something career woman having a bit of a crisis in her personal life. That's when her childhood imaginary friend Mary - voiced by Rachel Dratch - reappears in her life.
For more on the Elfman's take on the show, watch the video above.