Bryant has written a children's book series, won an Emmy and an Oscar.
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However, it was his investment in the sports drink BodyArmor back in 2014 that has been the most lucrative.
Bryant and Major League Soccer announced Wednesday that BodyArmor will be the official sports drink of MLS.
They made the announcement at Banc of California Stadium in Exposition Park, the home of Los Angeles FC.
The event also played host to 15 players from LAFC's under-12 academy, for a skills challenge on the field.
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Bryant, who played soccer in his own youth, said it was important to support the future of today's kids.
"They're our future. It's important to invest in them. They have dreams, they have ambitions of being a future MLS star. It's important we invest in them and educate them."
While Bryant is involved in has multiple business ventures he said the idea of being the owner of a professional sports franchise doesn't appeal to him.
"I've never been keen on jumping in and owning any sports franchise," he said. "I've had a couple come across my desk. I haven't really seriously considered them."