Officers responded shortly before 9:30 p.m. Saturday to reports of a man with a rifle near Kenmore Avenue and Wilshire Boulevard, the Los Angeles Police Department said.
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They attempted to make contact with the man and police opened fire, wounding the suspect, the LAPD said.
"The suspect ran from the officers" and police opened fire again, the LAPD said in a statement. "He then barricaded himself behind the stairwell of a building near the intersection of 7th Street and Vermont Avenue."
A SWAT team responded and attempted to get the suspect to come out from behind the stairwell, police said.
"SWAT utilized a remote-controlled tracked vehicle to assess the suspect's condition and attempted to retrieve the suspect's firearms," department officials said. "The tracked vehicle's arms were unable to retrieve the weapons."
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SWAT officers then deployed another type of controlled vehicle that was able to remove the man's firearms, "which allowed officers to approach the suspect and provide medical treatment," LAPD said.
The man was taken into custody shortly before 3 a.m. and was transported to a hospital in stable condition, police said.
No officers or bystanders were injured.