Firefighters responded to the area near Foothill Boulevard and Ramsdell Avenue just after 3:30 p.m. after the blaze was reported, according to the Los Angeles County Fire Department.
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At least 65 firefighters were dispatched to the fire, which quickly went to a second alarm and forced crews into a defensive mode, pouring water on the blaze from the exterior.
One firefighter was pulled from the blaze, but he appeared to be conscious and alert before he was transported to a hospital.
Crews gained the upper hand on the blaze within about 30 minutes, allowing firefighters to again move inside the structure to fully douse the flames. A knockdown was reported just before 5 p.m.
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No injuries were immediately reported. The cause of the blaze is unknown.
City News Service contributed to this report.