The incident occurred in the Temescal Valley-Corona area on the freeway near the Indian Truck Trail exit.
The driver in the car attacked was not hurt.
The suspect driver fled the scene, but police reportedly have their license plate number.
Traffic was backed up on the I-15 northbound in the area.
Road-rage incident causes traffic slowdown in Interstate 15
CORRECTION: This story was updated to note the correct location of the incident.