The three-vehicle collision was reported about 7:30 a.m. in the 2000 block of Beverly Boulevard.
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Video from AIR7 HD showed a Los Angeles Police Department SUV with visible damage to its right front fender and headlight area. Two civilian cars appeared to have collided nearly head-on.
The LAPD officer and three other people were taken to medical centers in unknown condition.
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The cause of the crash is under investigation.