The deputy, who hasn't been identified, was found a short distance away from the crash and was transported in an ambulance to a nearby hospital, according to authorities.
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Footage from the scene of the crash, which happened near Pico Canyon Road and Southern Oaks Drive, showed the patrol vehicle went off the road and into nearby bushes.
It's not immediately clear what led to the crash, but the deputy may have suffered a medical emergency.
A search for him ensued after the vehicle was found abandoned.
The deputy was later located about a mile away from the crash scene at a home in a residential neighborhood. He was transported in unknown condition.
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Details regarding how the deputy was found or why he left the crash site were not immediately released.