Long Beach PD officers responded to the collision in the 1900 block of E. Pacific Coast Highway at about 3:30 p.m.
Two pedestrians were struck and transported to nearby hospitals in unknown condition. It was unclear whether anyone in the vehicle was hurt.
A white SUV was seen on a curb and mangled next a building as officers investigated the scene.
PCH from Cherry to Gardenia avenues was closed until further notice.