The deputy, who has not been identified, was transported to a hospital. He is listed in stable condition, and his injury is described as a graze wound to the head.
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LASD said the shooting happened around 7:15 p.m. near 112th and Lorraine streets as the deputy was ambushed after responding to a robbery call. The deputy's dispatch call captured sounds of several bullets being fired.
Aerial footage from AIR7 HD showed the suspect vehicle's windshield riddled with bullets and a deputy cruiser peppered with shots.
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Deputies set up a perimeter in the area as the neighborhood was on lockdown, and the search for the suspect continued.
Authorities say the injured deputy is expected to make a full recovery.
It's unclear if more than one suspect is involved.